Most antibiotics belong to the emerging contaminants of the aquatic environment, whereat the use of antibiotics of last resort is strictly limited. Therefore, a robust and sensitive method for the analysis of these contaminants is necessary for environmental monitoring.
The aim of the project is to develop a method for the quantification of linezolid, tedizolid and tigecyclin in waste- and surface water by LC-MS/MS. The project also involves the use of online-SPE (solid phase extraction) and isotopically labeled compounds. The thesis can be written in English or German.